Coagulation · mg/L

D-dimer

D-dimer is a breakdown product of blood clots — it forms when the body breaks down a clot. Elevated means a clot formed (and broke down) somewhere, but it does not tell where.

Ranges we useESC / ISTH
RatingRangeWhat it means
Goodbelow 0.5 mg/LWithin range.
Worth improving0.5 – 1 mg/LSlightly elevated — nonspecific.
Talk to a doctor1 mg/L and aboveElevated — rule out thrombosis; consult.
Source: ESC / ISTH · 2019 ESC Guidelines on acute pulmonary embolism (starostno prilagojena meja); ISTH (enota FEU) · 2019 · open

Why it matters

ISTH: elevated with thrombosis (nonspecific); low helps rule out venous thrombosis.

If it’s low

Low D-dimer is useful — with a low clinical probability it strongly lowers the likelihood of a clot.

If it’s high

High D-dimer means recent formation/breakdown of a clot — but it is nonspecific: it is also raised by infection, injury, surgery, pregnancy, inflammation and age.

What to do

D-dimer is mainly a test to RULE OUT a clot and is not a screening test for healthy people. With symptoms (swollen, painful leg; sudden shortness of breath/chest pain) → URGENT care, do not wait for the result to be interpreted.

Read together with

Fibrinogen · Platelets

This content is for information only and is not a substitute for medical advice. Talk to your doctor about your results.

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