Tryptase (baseline)
Tryptase is an enzyme stored by mast cells (cells central to allergic reactions). Baseline (resting) serum tryptase reflects the total mast cell load in your body.
| Rating | Range | What it means |
|---|---|---|
| Good | below 11.4 µg/L | Baseline tryptase within range. |
| Worth improving | 11.4 – 20 µg/L | Mildly elevated — often hereditary (hereditary alpha-tryptasemia); monitor as appropriate. |
| Talk to a doctor | 20 µg/L and above | Elevated — further evaluation is warranted (mastocytosis/mast cell activation); seek advice. |
Why it matters
An elevated baseline value points toward mastocytosis or hereditary alpha-tryptasemia.
If it’s low
Low tryptase is of no clinical significance.
If it’s high
A persistently elevated baseline tryptase can be hereditary (common hereditary alpha-tryptasemia — harmless) or a sign of mastocytosis; kidney damage and some blood disorders also raise it. A consultation is needed to clarify.
What to do
A basally elevated value should be evaluated by a physician (allergist/hematologist) — it is often a harmless hereditary variant, but sometimes further work-up is needed. If you have had a severe allergic reaction, it is useful to measure tryptase both in the hours after the event and then at baseline.
Read together with
IgE (total) · Eosinophils (abs.)
Articles about this marker
This content is for information only and is not a substitute for medical advice. Talk to your doctor about your results.
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