Iron · %

Transferrin saturation

WHO/BSH: low (<20 %) supports iron deficiency; high suggests possible overload.

Ranges we useEASL
RatingRangeWhat it means
Talk to a doctorbelow 20 %Low saturation — possible iron deficiency.
Good20 – 45 %At optimum.
Talk to a doctor45 % and aboveHigh — possible iron overload; seek advice.

This marker also has 2 age- or sex-specific range sets in the app — the table shows the general one.

Source: EASL · EASL Clinical Practice Guidelines on haemochromatosis · 2022 · open

Why it matters

WHO/BSH: low (<20 %) supports iron deficiency; high suggests possible overload.

If it’s low

Low saturation means little available iron — often an early sign of deficiency, even before hemoglobin falls.

If it’s high

High saturation can indicate iron overload — important in hemochromatosis, where iron damages the liver, heart and pancreas.

What to do

Low: correct iron (after confirmation). High: do NOT add iron, check ferritin and, if needed, genetic testing for hemochromatosis.

Read together with

Ferritin · Transferrin · Iron · Hemoglobin

Part of the guide: Iron & ferritin →

Articles about this marker

This content is for information only and is not a substitute for medical advice. Talk to your doctor about your results.

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